"Pathologists always have to battle against their anxiety because the responsibility is always theirs alone to bear." - Professor Nakaguma Kaoru

I like that it's a different kind of medical drama where diagnosis and investigations became the main focus here instead of surgery or other medical aspects. I think it's a well made drama except for the unnecessary romance subplot between the patient and Hibako. Each episode has its own issue, and I particularly love episode 4. The episode 4 story was heartfelt and touching. Nagase's and Koyuki's performances in this episode were flawless. Check out the argument scene  between Kishi and Hosoki. I love the interactions between Kishi and the people around him like Morii, Miyazaki, Nakaguma and Hosoki.

The last two episodes however felt forced and rushed. The often repeated line in every episode used by Kishi got annoying after a while though. The background music was too loud for my taste. But the theme song, Fragile by TOKIO is love.

On to the actors' performances...Nagase Tomoya as the HBIC pathologist, Kishi Keiichiro is excellent. He is sarcastic, intelligent and sassy. Nagase's a versatile actor who can play any role given to him with aplomb whether it's a melancholic character like Okazaki Ritsu, a badass cop like Kurokouchi Keita, the mature elder brother like Ishihara Shintaro, a memory loss ex-soldier like Shimanto Taro or a red demon like Killer K. And did I mention that he is gorgeous? Takei Emi excels as the scatterbrained rookie doctor, Miyazaki Chihiro. Nomura Shuhei shines as the trusted lab technician, Morii Hisashi. They are ably supported by Koyuki, Kitaoji Kinya and Kanji Tsuda.

I hope that Fragile sequel (if there's any that is) will have more in depth character developments and backstories for the main characters because here they didn't explored much of them.