The same concept and storyline. The interpretation of the cases and how they come up with the result about who's who. Deduction and investigation skills type.
I think it's worth it to watch both seasons especially in chronological order. You would get your first impressions during the 1st season and get the feel of this unique and thrilling variety show. Although, there are some pacing issues with the first few episodes of season 1, it improved during its run and had a thrilling and great 1st season! Season 2 showed a lot of improvements and became more exciting and entertaining.
Actually, everything is roughly about the same. It's just the cast, the storyline, and the way they interpret the concept is different. So if you like this series or Who's the Murderer, you will definitely like Crime Scene. Crime Scene is the original and Who's the Murderer and Who's the Keyman is the China adaptation of it.
Both are detective variety shows where the cast has to find the truth to what has taken place. One difference is The Great escape is where the cast have to escape the crime scene/escape room whereas crime scene's cast plays roles within the actual 'fictional' crime to determine who the culprit was and to arrest them.
